12 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... only curative treatment ... #treatment #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... CK, normal biopsy ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
ED Treatment of 
Abnormal Uterine Bleeding 

Hemodynamically unstable 
Resuscitation 
 • ABCs! 
 • Fluids +
ED Treatment of ... pregnancy related cause ... increased risk of infection ... breast cancer IM ... Uterine #Bleeding #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... 500 mg QD until normal ... APML #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... to a preceding infection ... and cauda equina TREATMENT ... Hospital of Baltimore IM ... Syndrome #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... aplastic anemia Treatment ... #diagnosis #management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... filling +++ (risk of pulmonary ... of infections) ... syndrome #diagnosis #management ... #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis vs infection ... 50 in GCA, but normal ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... Exclude other causes ... failure - Infectious ... macrophages Treatment ... #diagnosis #management
Legionnaires' Disease
Clinical features:
 • Gl- nausea, vomiting, diarrhea
 • Hyponatremia
 • Elevated transaminases
 • CRP >100
respond to B-Lactams Treatment ... Other Legionella Infections ... Extra-pulmonary: ... Hospital of Baltimore IM ... Disease #diagnosis #management