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Ibuprofen. NSAID and non-selective COX-inhibitor used for the treatment of arthritis, pain, and fever. Originally discovered
Ibuprofen. ... #Pharmacology #Ibuprofen
False Positive Urine Drug Screens
Amphetamines - Amantadine, brompheniramine. bupropion, chlorpromazine, desipramine, ephedrine, isometheptene, isoxsuprine, labetalol, phentermine,
Barbituates - Ibuprofen ... hemp-containing foods, ibuprofen ... diphenhydramine, doxylamine, ibuprofen ... diphenhydramine, doxylamine, ibuprofen ... diphenydramine, ibuprofen
Summary of Agents Potentially Contributing to False Positives on Urine Drug Screens (UDS)
Marijuana Metabolites
 • dronabinol,
Barbiturates • ibuprofen ... thioridazine, ibuprofen ... mainly consist of ibuprofen
Therapeutic Advantages and Disadvantages of some NSAIDs
Salicylates: Aspirin, Salicylate salts, Diflunisal
Acetic acids: Indomethacin, Sulindac, Tolmetin
Propionic acids:
Propionic acids: Ibuprofen
Pericarditis can be seen on EKG with diffuse ST elevations without reciprocal changes along with diffuse
pericarditis is high dose ibuprofen
Medications that Can Cause False Positives on Drug Tests

Urine drug screens (UDSs) are simple to use,
medication like ibuprofen ... positives: • Ibuprofen ... positives: • Ibuprofen
Urine Drug Screens - Common drugs that may cause false positive tests 

Amphetamines:
Bupropion, Labetalol, Methylphenidate, Phenylephrine,
Diphenhydramine, Ibuprofen
NSAID Selectivity Spectrum
COX-2 Selective NSAID - Celecoxib
 • Increased risk for CV events
 • Decreased risk
Nonselective NSAIDs - Ibuprofen
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Acetaminophen, Thiazides, Ibuprofen
NSAID Dosing in CKD
 • Carboxylic Acids: Salsalate, Choline Mg trisalicylate
 • Acetic Acids: Indomethacin, Tolmetin,
Propionic Acids: Ibuprofen