23 results
NSAIDS and COX Selectivity

Relative selectivity of some commonly used NSAIDs. Data shown as the logarithm of
NSAIDS and COX Selectivity ... Relative selectivity ... COX-1 Selectivity ... Naproxen, Tolmetin, Ibuprofen ... #pharmacology #selectivity
NSAID Selectivity Spectrum
COX-2 Selective NSAID - Celecoxib
 • Increased risk for CV events
 • Decreased risk
NSAID Selectivity ... Nonselective NSAIDs - Ibuprofen ... effects #NSAIDs #selectivity
False Positive Urine Drug Screens
Amphetamines - Amantadine, brompheniramine. bupropion, chlorpromazine, desipramine, ephedrine, isometheptene, isoxsuprine, labetalol, phentermine,
Barbituates - Ibuprofen ... hemp-containing foods, ibuprofen ... diphenhydramine, doxylamine, ibuprofen ... diphenhydramine, doxylamine, ibuprofen ... diphenydramine, ibuprofen
Summary of Agents Potentially Contributing to False Positives on Urine Drug Screens (UDS)
Marijuana Metabolites
 • dronabinol,
Barbiturates • ibuprofen ... thioridazine, ibuprofen ... mainly consist of ibuprofen
Pericarditis can be seen on EKG with diffuse ST elevations without reciprocal changes along with diffuse
pericarditis is high dose ibuprofen
Heparin and Low Molecular Weight Heparin (LMWH)–Mediated Inactivation of Thrombin or Factor Xa 
 - Interaction
- LMWH selectively
Medications that Can Cause False Positives on Drug Tests

Urine drug screens (UDSs) are simple to use,
medication like ibuprofen ... positives: • Ibuprofen ... positives: • Ibuprofen
Therapeutic Advantages and Disadvantages of some NSAIDs
Salicylates: Aspirin, Salicylate salts, Diflunisal
Acetic acids: Indomethacin, Sulindac, Tolmetin
Propionic acids:
Propionic acids: Ibuprofen
Acyclovir - Pharmacology Summary

 • Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of
Nucleoside analog - selectively
Urine Drug Screens - Common drugs that may cause false positive tests 

Amphetamines:
Bupropion, Labetalol, Methylphenidate, Phenylephrine,
Diphenhydramine, Ibuprofen