1010 results
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Hypercoagulable Workup Algorithm ... maternal chromosomal causes ... 1 Antibodies, IgG ... Hypercoagulable #Workup #Algorithm ... #diagnosis #hematology
Subtypes of Serum Proteins

Pre-albumin (Transthyretin)
Albumin
Globulins
 • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Transferrin • Gamma: IgM ... , IgG, IgA, RF, ... Proteins #Subtypes #algorithm ... classification #Types #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... , IgG, IgM (CVID ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
AIHA: - 70%; IgG ... mediated - DAT: IgG ... AIHA: - 20%; IgM ... mediated - DAT: IgG ... Pathophysiology #diagnosis #hematology
Cryoglobulinemia Classification Types

Type 1: Monoclonal IgM (rarely IgG/lgA)
 • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
(rarely IgG/lgA ... and polyclonal IgG ... and polyclonal IgG ... and polyclonal IgG ... Classification #Types #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Differential Diagnosis Algorithm ... and non-hematologic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... or IgG isotype ... (rarely IgD or IgE ... #Significance #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Non malignant hematologic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
Suggested algorithm ... small (<1.5 gm/dL) IgM ... low-risk MGUS (IgG ... #MGUS #Biopsy #algorithm ... diagnosis #management #hematology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vasculitis: - Ig ... vasculitis with IgG ... /IgM deposits ... Vasculitis #skin #dermatology ... #rheumatology #