36 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Acquired • Immune ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... effect following treatment ... Iron deficiency anemia ... #Algorithm #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential Diagnosis ... hemolytic anemia ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... • Others Non-lmmune ... #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
1) DIAGNOSE AIHA ... • Anemia: macrocytic ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Hemolysis: • Immune-mediated ... Extravascular #Causes ... #hematology #anemia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
cell-mediated immune ... Weight Loss • Can cause ... Lymphohistiocytosis • Anemia ... #management #treatment ... #infectiousdiseases
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... and petechiae Causes ... Treatment: ... #oncology #hematology ... #diagnosis #management
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... cell disease Rheumatology ... involvement Sepsis - Immuno-compromise ... Pathway #Child #Peds ... #Pediatrics #Diagnosis