320 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint ... Treatment #Immune ... #Pharmacology #Oncology
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
invasion, evasion of immune ... Pathophysiology #Oncology
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Side Effects - Immune-related ... - Immune-related ... - Most immune-related ... AdverseEffects #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... HCV - HIV • Immune ... Aplastic #Anemia #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... diagnosis #workup #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Erythema nodosum • Immune ... classification #hematology #oncology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Bowman's space) Immune-Complex ... • Presence of immune ... deposits Pauci-lmmune ... • Minimal immune
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... HEMATOLOGIC ONCOLOGIC ... STRUCTURAL ONCOLOGIC ... ) METABOLIC ONCOLOGIC ... #emergencies #oncology
Management of Immune Thrombocytopenia (ITP) . 

#Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune ... Thrombocytopenic #Purpura #Immune
Summary Table of Paraneoplastic Syndromes

#Diagnosis #Oncology #Paraneoplastic #Syndromes #Table
#Diagnosis #Oncology