127 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... workup for specific symptoms ... for secondary causes ... glucocorticoid treatment ... #Differential #diagnosis
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
It is caused by ... connective tissue disorders ... TreeInBud #Sign #diagnosis ... #clinical #radiology ... #ChestCT #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Headache, Movement disorders ... , Seizure disorders ... Disease, PRES Pathophysiology ... autoantibodies that will cause
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Lysosomal storage disorder ... in macrophages Diagnosis ... in GBA1 gene Clinical ... #Signs #Symptoms
Assessment of the Child with Chronic Asthma
Are there other allergic disorders?
 - Allergic rhinitis
 - Eczema,
other allergic disorders ... Other causes should ... and frequency of symptoms ... rhinitis needing treatment ... Asthma #Assessment #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... pattern of spread, B symptoms ... Responsive to Treatment ... Classification #pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... improvement in symptoms ... endpoint of all-cause
Hordeolum vs Chalazion

Hordeolum (Stye):
 • Location: Most commonly found at or near an eyelash follicle
 •
eyelash follicle • Cause ... of the lids • Symptoms ... upper lid • Cause ... eyedrops, surgery #Clinical ... #Diagnosis #Management
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Non-hemolytic Disorders ... as jaundice on clinical ... examination; nonspecific symptoms ... and stress may cause ... bilirubin #hepatology #diagnosis
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Pathogenesis and Clinical ... mood - Primary treatment ... MoodDisorders #Diagnosis ... #Pathophysiology ... #Signs #Symptoms