1861 results
differential management causes pocus algorithm radiology ultrasound signs cardiology symptoms pathophysiology pharmacology neurology pulmonary syndrome table hematology treatment dermatology physicalexam
Pulmonary complications of targeted therapy -Immune checkpoint inhibitors (e.g. pembrolizumab) -Pneumonitis is uncommon (~5% of patients) but can
Immune checkpoint inhibitors ... -It’s a diagnosis ... associated with a clinical ... unclear if this is a drug ... #Clinical #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... accumulation of clinical ... Assessment • Clinical ... immune deficiency, Drugs ... Anti-IFN-y and JAK inhibitors
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Pathogenesis and Clinical ... Group A Strep - Drugs ... necrosis factor a inhibitors ... Pathophysiology #Diagnosis
Causes of Small Bowel Ulceration The diagnosis of IBD can’t be made or excluded by biopsies alone
Ulceration The diagnosis ... this requires clinical ... Adenocarcinoma • Drugs ... Aspirin, Checkpoint inhibitors ... SmallBowel #Ulceration #diagnosis
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction. PDE5 inhibitors enhance an erection that is
PDE5 inhibitors ... are usually the drugs ... Drug interactions ... depending on the drug ... medications #dosing #drugs
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Antimicrobials Drug-induced ... Tyrosine kinase inhibitors ... panitumumab) #Drugs ... #differential #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Drugs: Direct or ... drugs (e.g. direct ... Inhibitors: Non ... Prolonged #Causes #diagnosis
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Drugs a. ... Direct Xa inhibitors ... Drugs a. ... drugs e.g. direct ... Prolonged #Causes #diagnosis
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
are both CYP3A4 INHIBITORS ... metabolism of drugs ... and a 3A4 inhibitor ... is just a 3A4 inhibitor ... both have lots of drug
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Direct renin inhibitor ... Angiotensin-converting enzyme (ACE) inhibitors ... • Calcineurin Inhibitors ... #differential #diagnosis
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