21 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... #diagnosis
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... ascites removed • Acute ... kidney injury ( ... #Cirrhosis #treatment ... #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Vancomycin Associated Acute ... • Drug induced acute ... • Treatment includes ... #pharmacology #toxicology ... #diagnosis #management
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... progress to MDS or acute ... #management #treatment ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
immunosuppression • Acute ... with severe liver injury ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... - Acute Bleeding ... Chronic Management ... #Management #treatment ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... pattern of liver injury ... Hepatitis (eg Viral) Management ... regarding need for treatment ... #Management #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... Renal Failure Treatment ... #management #hematology