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hematology differential management anemia comparison oncology table aflp bleeding bruising hellp intravascular mds myelodysplastic obstetrics pregnancy thrombocytopenia ttphus abnormal activation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Proteins - Acquired ... #Algorithm #Causes ... #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... of Factor IX Acquired ... Acute DIC - Septic shock ... table #comparison #diagnosis ... #hematology #deficiency
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Syndrome - Diagnosis ... vonWillebrand #Syndrome ... #Diagnosis #Management ... #treatment #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... presents with coagulation ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
dysfunction (16%) • Shock ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... presents with coagulation ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... intravascular coagulation ... ) - HELLP syndrome ... #hematology #anemia
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Acquired deficiency ... Pre-analytical cause ... #diagnosis #differential ... #hematology #coagulation
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