10 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... their Disease Associations ... hepatitis Anti-CCP ... diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Citrullinated Peptide (CCP ... RheumOnePagers #Autoantibodies ... diagnosis #associations ... #table
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Acute DIC - Septic shock ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Can also be measured ... #Antinuclear #autoantibodies ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Causes and clinical associations ... , Hypotension, shock ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Entities That Can ... macular Vasculitis) Autoantibodies ... angioedema • vWD • acquired ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
perstans • A form of acquired ... well-described associations ... Classic association ... Erythemas #comparison #table ... #differential #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Manifestations: - CRP ... months) and of autoantibodies ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... stones caused by Ca2 ... New York Heart Association ... • Hypovolemic shock ... #Medications #Table
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Myoglobin Association ... Dermatomyositis: • ILD was diagnosed ... Dermatomyositis #diagnosis ... #dermatology