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differential management erythematosus systemic antinuclear autoimmune myositis oncology patterns vasculitis activation autoantibodies behcet chronic classification cll disease leukemia leukostasis lymphocytic
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... ), Sjogren's Syndrome ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... ), Sjogren's Syndrome ... , Sjögren Syndrome ... #rheumatology #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
: - Arthritis ... Auto-Antibodies ... : - ANA 95-100% ... and Lupus Mimickers ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Non-autoimmune rheumatologic ... : • Symptoms limited ... #Rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms ... #Pathophysiology ... #Diagnosis #Signs
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... anti-synthetase syndrome ... arthritis (19% ... Can also see mechanics ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... : SLE, Reactive ... #signs #symptoms ... #rheumatology #
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... , breast CA - Hematologic ... - Lupus - Leukemia ... #diagnosis #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
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