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differential lupus management classification vasculitis antibodies disease monoarthritis monoarticular msk myositis oncology patterns polyarthritis polyarticular sjogrens workup activation algorithm arthropathies
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Juvenile Idiopathic Arthritis ... Syndrome (SS), ... (SLE), Systemic ... @AnnKumfer #Antinuclear ... #patterns #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... (SLE), Systemic ... #patterns #rheumatology ... #diagnosis #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
’s syndrome) Aseptic ... autoimmune disease ... Lupus Erythematosus ... (SLE), should have ... other symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... lupus erythematosus ... (SLE) Signs / ... #Pathophysiology ... #Diagnosis #Signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rheumatologic diseases ... Joint pain • Swan ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... anti-synthetase syndrome ... arthritis (19% ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
cutaneous lupus • Arthritis ... in at least 2 joints ... Thrombocytopenia, Autoimmune ... Classification #Criteria #SLE ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... : - Arthritis ... #Erythematosus ... #signs #symptoms ... #differential #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
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