22 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
5-10x normal - Chronic ... normal - Hemolysis, NASH ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
) - Differential ... Cirrhosis • Chronic ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... Diagnosis #hepatology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Algorithm. ... Causes: 1) Exfoliative ... #Dermatology #Rash ... #Differential # ... Ddxof
Chest Pain - Differential Diagnosis Algorithm
Cardiovascular Causes:
 - Outflow Obstruction
     • Aortic
Chest Pain - Differential ... Diagnosis Algorithm ... Aortic Stenosis - Ischemic ... • Muscular Injury ... #Diagnosis #Algorithm
Causes of Chronic Pelvic Pain (> 6 months in duration) - Differential Diagnosis Algorithm
Co-morbidities:
 • Somatization
Causes of Chronic ... Diagnosis Algorithm ... trigger points) • Injury ... #Pain #Differential ... #Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Others #LFTs ... Diagnosis #Algorithm ... #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... • Vascular: Ischemic ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Other • ATN: Ischemia ... Pigment, Protein) • AIN ... #causes #algorithm
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... sulfa-drug - Skin pain ... #Dermatology #Rash ... #Differential # ... Ddxof