14 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... ITP • SLE • CLL ... #Causes #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... • Most common leukemia ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... Consider sickle cell ... #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Leukemia • Idiopathic ... Workup: • Complete ... blood count with differential ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Responsive to Treatment ... Treated Like Acute Leukemias ... pathophysiology #Hematology ... #algorithm