75 results
management causes algorithm rheumatology anemia neurology syndrome cardiology oncology workup classification hepatology coagulation disorders hepatitis systemic abnormal aih autoimmune bleeding
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g ... inhibitory drugs (e.g ... specific inhibitor (e.g ... hematology #coagulation
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
- Differential ... Diagnostic Schema ... inflammation (e.g ... hypovolemia), Meds/Treatments ... #Schema #Differential
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
to one factor e.g ... inhibitory drugs e.g ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... PT and/or aPTT) ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bleeding disorder Clinical ... INR • Normal aPTT ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... hemophilia type (e.g ... #Management #treatment ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #Management #treatment ... #hematology #differential
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
• Provoked (e.g ... screening, CBC, aPTT ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
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