29 results
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
chronic kidney disease ... deficiency - Probable bone ... Eric Strong @DrEricStrong ... - Strong Medicine ... Underproduction #Algorithm #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... • Mechanism: ischemic ... Pain #SickleCell #Disease ... #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... Eric Strong @DrEricStrong ... - Strong Medicine ... differential #diagnosis #causes ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Chronic kidney disease ... Hypogonadism • Bone ... Eric Strong @DrEricStrong ... - Strong Medicine ... Production #Index #hematology
Causes of Nausea and Vomiting - Differential Diagnosis Framework

Chemoreceptor Trigger Zone/Area Postrema:
 • Drugs:
	- Chemo agents
	-
Causes of Nausea ... Chemoreceptor Trigger Zone ... Metabolic: - Uremia ... - Addison’s disease ... • Mesenteric ischemia
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Constant Pain (Ischemia ... • Sickle Cell Anemia ... Peripheral Vascular Disease ... fractured long bone ... #Orthopedics #Causes
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... g/dl LLN B - Bony ... more: • Clonal bone ... Causes of false- ... MGUS #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... - Strong Medicine ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
HAS-BLED scores for stroke ... 2 V Vascular disease ... Bleeding history/anemia ... CHADS2VASc #HASBLED #Comparison ... AFib #Diagnosis #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Drug induced - Bone ... - Hemolytic anemia ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology