28 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... prevention (statin for CVA
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm
Look for surgical abdomen
Upper quadrant: R/O cardiac,
Acute Abdominal Pain ... musculoskeletal causes ... genitourinary causes ... • Mesenteric ischemia ... • Sickle cell anemia
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Cell Disease Vaso-occlusive ... : ischemic pain ... #SickleCell #Disease ... #hematology
Causes of Dyspnea - Differential Diagnosis Algorithm
Cardiac:
 • Dysrhythmia
 • Ischemia
 • Cardiomyopathy
 • Valvular disease
Causes of Dyspnea ... Dysrhythmia • Ischemia ... Superior vena cava ... • Anxiety • Anemia ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... Eric Strong @DrEricStrong ... - Strong Medicine ... differential #diagnosis #causes ... #hematology
Causes of Nausea and Vomiting - Differential Diagnosis Framework

Chemoreceptor Trigger Zone/Area Postrema:
 • Drugs:
	- Chemo agents
	-
Causes of Nausea ... Metabolic: - Uremia ... - Addison’s disease ... • Stress • Pain ... • Mesenteric ischemia
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Causes - Differential ... • Colorectal CA ... pregnancy • Ovarian CA ... Chronic mesenteric ischemia ... • Mesenteric ischemia
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain ... (Ischemia) - ... • Sickle Cell Anemia ... Peripheral Vascular Disease ... #Orthopedics #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... - Strong Medicine ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... Pathophysiology of disease ... organs leading to ischemia ... , necrosis and pain ... Complications #Hematology