35 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... Liver #Injury #hepatology ... #differential #diagnosis
Heparin-Induced Thrombocytopenia (HIT) Evaluation Algorithm

- Dr. Josh Farkas @PulmCrit

#4TScore #HITT #Algorithm #HeparinInduced #Thrombocytopenia #Diagnosis #Criteria #Hematology
Heparin-Induced Thrombocytopenia ... HeparinInduced #Thrombocytopenia ... #Diagnosis #Criteria ... #Hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy #thrombocytopenic ... HemolyticUremicSyndrome #HUS #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury - Ichemic ... #Differential #Hepatology ... #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
that will cause ischemia ... cyclophosphamide • Ischemic ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
ferritin, Anemia, Thrombocytopenia ... IL-2 receptor Diagnostic ... ): Molecular diagnosis ... Lymphohistiocytosis #diagnosis ... #hematology #criteria
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... liver injury) • Ischemic ... #Differential #Diagnosis ... #hepatology #transaminitis
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
Heparin-Induced Thrombocytopenia ... HeparinInduced #Thrombocytopenia ... #Diagnosis #Criteria ... #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Drugs/Toxins • Ischemia ... Others #LFTs #Hepatology ... #Differential #Diagnosis