14 results
Evaluation of Patients with Anemia

Microcytic, Normocytic, Macrocytic, Hemolytic (Intravascular and Extravascular)

#Diagnosis #Anemia #Workup #Macrocytic #Microcytic #Normocytic
, Macrocytic, Hemolytic ... (Intravascular ... and Extravascular ... Anemia #Workup # ... #Algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... and Intravascular ... Hemolysis - Differential ... Diagnosis Algorithm ... Differential #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... - Disseminated intravascular ... hemoglobinuria (PNH) Extravascular ... #Hemolytic #Intravascular ... #diagnosis #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... loss: Intravascular ... (not extravascular ... ) hemolysis, Intensive
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Morphology Atlas • Microcytic ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... , Disseminated intravascular ... #differential #
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
to Anemia - Differential ... inflammation) • Iron ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Diagnosis #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Under 80 = microcytic ... acute blood loss, hemolysis ... #Algorithm #Diagnosis ... #Workup #Hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Pancytopenia - Differential ... Diagnosis Algorithm ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm ... #hematology #workup
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... autoimmune hemolytic ... #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... udaygulati #Hemolytic ... #Anemia #Differential