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causes algorithm rheumatology oncology thrombocytosis activation alopecia approach calculation clinical cll common compared comparison cvid erythemas foot hair hairloss hemeonc
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
of Chronic Disease ... of Chronic Disease ... , Chronic Infection ... #MCV #Classification ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... disorders • Celiac disease ... Iron deficiency anemia ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 ... deficiency • Fanconi’s anemia ... Systemic lupus erythematosus ... deficiency Infections ... #Diagnosis #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
parvovirus B19 infection ... Dermatomyositis Erythema chronicum ... Sarcoidosis #dermatology ... #skin #rashes #differential ... #diagnosis #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... • Anemia of Chronic ... Disease • Marrow ... #Classification ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... : Chronic infections ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
kidney disease, ... (e.g. cancer, infection ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... Causes: • Liver disease ... drug induced • Infections ... #classification ... #hematology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... - HIV infection ... hemolytic anemia ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... autoimmune hemolytic anemia ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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