14 results
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... drug reactions) Conjugated ... excretion of bilirubin conjugates ... postoperative jaundice ... neoplasms #Jaundice
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... II) Hepatic - Conjugated ... on Ultrasound Biliary ... Gallstones • Biliary ... Cholangitis #Jaundice
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... @AmyChung #Jaundice ... #Pathophysiology ... #Differential #Unconjugated
Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
for Liver and Biliary ... erythema 2) Face: Jaundice ... Xanthelasma and jaundiced ... Bruising, Edema #biliary ... liver #disease #signs
Diseases of the Biliary Tract
Asymptomatic gallstones - Asymptomatic
Symptomatic gallstones - Biliary pain
Cholesterolosis of gallbladder - Usually
Diseases of the Biliary ... fever, Murphy sign ... cholecystitis - Biliary ... Asymptomatic or biliary ... pain, jaundice,
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... quadrant discomfort Signs ... : Jaundice, Xanthelasmata ... #PBC #Primary #Biliary
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... failure PBC Signs ... hyperpigmentation • Jaundice ... No extrahepatic biliary
Clinical Signs of Pancreatic Cancer
Jaundice
Cachexia
Depression
Vomiting from duodenal obstruction
Lymphadenopathy
Palpable gallbladder (Courvoisier's sign)
Hepatomegaly (extrahepatic biliary obstruction/secondary deposits)
Scratch marks
Clinical Signs of ... Pancreatic Cancer Jaundice ... (Courvoisier's sign ... (extrahepatic biliary ... marks (obstructive jaundice
Courvoisier Sign or Courvoisier-Terrier Sign

States that in a patient with painless jaundice & an enlarged gallbladder
Courvoisier Sign ... Courvoisier-Terrier Sign ... with painless jaundice ... pancreatic or biliary ... Courvoisier #Terrier #Sign
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
processes like primary biliary ... erythematosus (SLE) Signs ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs