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diagnosis differential hematology management anemia algorithm workup hepatitis nephrology gastroenterology cirrhosis classification hemolysis treatment alcoholic blood fever glomerular hepatopulmonary high
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Anemia #Laboratory ... #Testing #workup ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... cold agglutin disease ... e.g. sickle cell disease ... Extravascular #Causes ... differential #diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... a clinical and laboratory ... Microangiopathic hemolytic ... coagulation and other testing ... #anemia #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... Algorithm #workup #hematology ... #testing
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Production • Hemolysis ... Cholangitis #Jaundice ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Serum Sickness Hemolytic ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes ... #Hematology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
) • Onset of jaundice ... metabolic liver disease ... (Wilson disease ... Presence of atypical laboratory ... Hepatitis #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Hepatitis - Onset of jaundice ... metabolic liver disease ... (Wilson disease ... Presence of atypical laboratory ... Hepatitis #Diagnosis #Hepatology
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... • Asplenia Laboratory ... blood loss • Hemolytic ... End-stage renal disease ... HbA1c #HgbA1c #Laboratory
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic Causes ... : • Liver disease ... udaygulati #Hemolytic ... classification #hematology
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