31 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... 48% (light chain ... #Management #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
1 or more: • Clonal ... serum free light chain ... of MM), light chain ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... • Clinical features ... Differential Diagnosis ... #NonHodgkins #comparison ... #oncology #diagnosis
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Ig deposition disease ... #Differential #Diagnosis ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... constitutional symptoms ... type) < 3 g/dL • Clonal ... proliferative disorder • Clonal ... #diagnosis #oncology
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated diseases ... predominance) • Clinical ... and spleen • Clinical ... features: Effusion, B symptoms ... #comparison #diagnosis
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... and duration of symptoms ... angioedema Other symptoms ... #rheumatology # ... comparison #table
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
cytometry → >500/uL clonal ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... • Signs of VTE ... node biopsy • Clinical ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Hyperreflexia, Clonus ... Signs and symptoms ... patients with clinically ... stimulation Clinical