30 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... component of Nephron: CHF ... hyporenin hypoaldo, hyperkalemic ... KidneyDisease #nephrology ... #Effects #pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
Heart Failure (CHF ... depot iron] Treatment ... Heart #Failure #CHF ... #pharmacology # ... pathophysiology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... • NSAIDs • ACE ... Food - Avoid in CRF ... potassium #high #nephrology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
INDICATION: Treatment ... of Hyperkalemia ... patients with CKD, HF ... ACE inhibitors, ... #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Na delivery): CHF ... Ca-gluconate or 1g CaCl ... Redistribution Treatments ... #potassium #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Migraine - Preventative Treatments

 • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin
 • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
- Preventative Treatments ... Beta-blockers, ACE ... #Preventative #Treatment ... prophylaxis #prevention #pharmacology ... #neurology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... • NSAIDs • ACE ... Food - Avoid in CRF ... potassium #high #nephrology