6571 results
Abnormal Lipid Profiles - Differential Diagnosis Algorithm

Increased Cholesterol and Triglycerides 
 - Genetic Causes
- Differential Diagnosis ... Androgens Increased LDL ... ApoB-100 • LDLr ... • Familial LPL ... #Differential #Diagnosis
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Expression → ↑ VLDL ... /Secretion → ↑ LDL ... Production → ↑ LDL ... Receptors → ↑ LDL ... Clearance → ↓ Plasma LDL-C
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis
Spontaneous Bacterial Peritonitis
 • Cirrhosis (high SAAG)
PMN > 250 • Treatment ... protein > 1 g/dL ... glucose < 50, LDH ... Positive Culture • Treatment ... Secondary #Peritoneal #diagnosis
Ranson's Criteria in Pancreatitis 
At Admission: 
 - Age > 55 years 
 - WBCs >
Glucose > 200 mg/dl ... - LDH > 350 ... BUN rise > 5 mg/dl ... Calcium < 8 mg/dl ... #Pancreatitis #Diagnosis
Risk factors for atherosclerosis

Modifiable risk factors:
 - Dyslipidemia (elevated LDL, decreased HDL)
 - Tobacco smoking
 -
Dyslipidemia (elevated LDL ... , decreased HDL)
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Syndrome (TLS) and Treatment ... acid ≥ 8.0 mg/dL ... hypocalcemia Treatment ... Hyperkalemia - Standard treatment ... Syndrome #TLS #diagnosis
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) DIAGNOSE ... indirect bilirubin, ↑ LDH ... Hemolytic #Anemia #diagnosis ... #management #treatment
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... Purpura (TTP) Diagnosis ... HUS) Treatment ... the ICU (age, LDH ... soon as TTP is diagnosed
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
- Differential Diagnosis ... Algorithm • 12-13 g/dL ... reticulocyte count, LFTs, LDH ... Differential Diagnosis ... #Differential #Diagnosis
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Serum uric acid, LDH ... Uric acid ≥ 8 mg/dL ... Calcium ≤ 7 mg/dL ... of the above Treatment ... Lysis #Syndrome #diagnosis