130 results
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... proteins domain: Low ... C3 or low C4, Low ... C3 and low C4
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... thrombosis and/or blood-brain ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... 60-80% - Low ... life-threatening • Treatment ... Management #Summary #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... Erythematosus Clinical ... Immunologic Criteria CLINICAL ... anticoagulant - Low ... #Diagnosis #Rheumatology
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Guidelines - Low ... Tapering DMARDs - Treatment ... Guidelines #management #treatment ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... in >90% - Low ... 40, F:M 9:1 • Clinical ... 60-80% - Low ... life-threatening • Treatment
Immunosuppressive Medications in Systemic Lupus Erythematosus (SLE)
 - MTX (oral, subcutaneous)
 - AZA (oral) 
 -
Medications in Systemic Lupus ... Cyclophosphamide (CYC) (iv; low ... Medications #Systemic #Lupus ... Erythematosus #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low ... Skin Disease Classification ... Malignancy (e.g. hematologic ... , lymphopenia, low
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
S - Systemic Lupus ... Hypocomplementemia #Low ... #differential #hematology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... Nephritis #Management #treatment ... #management #rheumatology