95 results
Statin Intensities

Basic refresher of statin intensities! One common thing I see a lot is patients being
Statin Intensities ... common thing I see ... a lot is patients ... High #Moderate #Low ... #Pharmacology #
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... proteins domain: Low ... C3 or low C4, Low ... C3 and low C4 ... #Criteria #SLE
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Guidelines - Low ... Tapering DMARDs - Treatment ... Guidelines #management #treatment ... #rheumatology
LOW MOLECULAR WEIGHT HEPARIN (LMWH) DOSING RECOMMENDATIONS (Enoxaparin and Dalteparin):
 - VTE PROPHYLAXIS
 - VTE TREATMENT
LOW MOLECULAR WEIGHT ... PROPHYLAXIS - VTE TREATMENT ... #Prophylaxis #Pharmacology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... 60-80% - Low ... life-threatening • Treatment ... Management #Summary #rheumatology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
NH4+ (relatively low ... #Lactulose #pharmacology ... mechanism #ammonia #hepatology
Antibiotic Tissue Penetration

Blood Brain Barrier: Penicilins (IV), 3rd & 4th generation Cephalosporins (IV), Meropenem, TMP-SMX, Metronidazole,
Penetration Blood Brain ... (hydrophilic, low ... ), Vancomycin (low ... inactivated by low ... #Penetration #pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... constitutional symptoms • Treatment ... 60-80% - Low ... life-threatening • Treatment ... comparison #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Puncture, EEG Treatment ... Erythematosus #SLE ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
Drugs with low CNS ... Perfusion #CSF #Pharmacology ... #Classification