60 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... diagnosed annually in US ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... Summary Clinical ... marrow plasma cells ... >10% plus one of ... #oncology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... of fluid &/or pus ... accumulation of pus ... #Mastoiditis #pathophysiology ... symptoms #diagnosis #otology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... Constitutional Syndromes ... Aplastic #Anemia #oncology ... hematology #diagnosis #management
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... harmful -> Th Cells ... macrophages, mast cells ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... APML #diagnosis #management ... #hematology #oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Calcium ≤ 7.0 mg/dL Clinical ... #TumorLysis #Syndrome ... TLS #diagnosis #management ... #oncology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... Burkitt, SCLC Cells ... #TLS #Pathophysiology ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... : • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
contractio -> LUTS ... Progression of LUTS ... testicular Leydig cells ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology