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diagnosis hematology differential causes bruising dic disseminated hepatology intravascular management workup anatomy anticoagulants anticoagulation aptt blanching bruise chemistry disease disorders
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
) - Bleeding Tendency ... ) - No Bleeding ... #Prolonged #PPT ... #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... DrEricStrong #Algorithm ... #Coagulation #Abnormal ... #APTT #Laboratory
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Findings: • Bleeding ... venipuncture sites Laboratory ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... ) ABNORMAL PT ... PT/ABNORMAL PTT ... fibrinogen levels, and testing
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Anticoagulants on Coagulation ... Tests PT / INR, ... Anticoagulation #Testing ... #Diagnosis #Laboratory
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... #Bleeding #Bruising ... Differential #Diagnosis #Algorithm
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... consumption of coagulation ... using INR use PT ... diagnosis #hematology #laboratory
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... bruising • Skin bleeding ... • Prolonged bleeding ... GI. uterine) Laboratory ... PT/INR • Normal
Paracentesis Anatomy Landmarks Don't hit the inferior epigastric artery!!! Go 2cm below the umbilicus in the midline
spine Overall coagulation ... in the setting ... cirrhosis, despite abnormal ... tests of coagulation ... Prolonged PT) because
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Differential Diagnosis Algorithm ... succenturiate lobe • Abnormal ... intravascular coagulation ... (DIC) • Anti-coagulation ... PostPartum #Hemorrhage #PPH
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