16 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
with excreting potassium ... Antagonists), all ... will increase potassium ... , just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... the cell, serum potassium ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... vs. 1) • Fewer ACS ... Benefits #SickleCell #pathophysiology ... #pharmacology
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Cruciate Ligament (PCL ... structures, such as the ACL ... Posterior draw test, - Lachman ... Posterior draw test, + Lachman ... #MSK #Sports #pathophysiology
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
and urokinase act ... -antiplasmin), act ... Fibrinolysis #Pathway #Pathophysiology ... #Plasminogen #Pharmacology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
) MECHANISM: Potassium ... patiromer) is a potassium ... ACE inhibitors, ... Veltassa #Patiromer #Potassium ... #Hyperkalemia #Pharmacology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Diuretics #Pharmacology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... Tubules #Table #Pharmacology