18 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... #decisionaid #cardiology ... #hematology #warfarin
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... endpoint of all-cause ... heartfailure #diagnosis #management ... #cardiology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Anticoagulation (case ... by case) • Surgery ... Syndrome #Treatment #management ... #pharmacology # ... rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... 100 mg/m2) : in case ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... #Pathophysiology ... #cardiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Acute Atrial Fibrillation - Initial Options for Rate Control
Diltiazem IV
 •  Rapid onset and rapidly
IV bolus can cause ... • Does not cause ... Rate #Control #pharmacology ... #management #cardiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
inotropy) ACCP Cardiology ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology ... #cardiology