14 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... Acute onset of skin ... in the acute phase ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Fatigue • Acute ... Lymphocytic Leukemia (CBC ... Algorithm #Causes #Hematology ... #Oncology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... auto-reactive B and CD ... , Carditis #Acute ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Rare: DAH, acute ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... Clinical Signs/Symptoms ... not feasible CMC ... Diagnosis #Management #dermatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Vmphocytosis on routine CBC ... Splenomegaly 5) Symptoms ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphocytosis on CBC ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... - ACS, AKI, acute ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ALL (Acute Lymphoblastic ... Blasts APML (Acute ... #Leukemia #Hematology ... #Oncology #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... transfusion • Pathophysiology ... At least 3 of (Acute ... Transfusion #Reactions #hematology