16 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Fatigue • Acute ... Leukemia (CBC with ... Lymphocytes) ... - Monoclonal Lymphocytes ... Causes #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Vmphocytosis on routine CBC ... lymphadenopathy 3) B symptoms ... Splenomegaly 5) Symptoms ... Constitutional symptoms ... #Leukemia #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphocytosis on CBC ... surface molecules: CD5 ... ’s lymphoma or acute ... diagnosis #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ALL (Acute Lymphoblastic ... Lymphadenopathy AML (Acute ... Blasts APML (Acute ... Leukemia #Hematology #Oncology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... Acute onset of skin ... in the acute phase ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... auto-reactive B and CD ... Sydenham's Chorea Lymphocytes ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral ... Syndrome Acute ... during transient CD4 ... • Leukocyte-lymphocyte ... Photophobia • Lymphocytic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
cells absent, lymphocyte ... Rich, Lymphocyte ... pattern of spread, B symptoms ... Treated Like Acute ... Classification #pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
regeneration, diffuse CD8 ... + T lymphocytes ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Rare: DAH, acute ... Diagnosis: >3 symptoms ... , Anaphylaxis, Acute ... management #hematology #oncology