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hematology diagnosis differential hemolytic hemolysis management algorithm causes extravascular hemeonc intravascular agglutinin anemias bandemia cbc chronic cll cold disease hemophagocytic
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... MatthewHoMD #Autoimmune ... #Hemolytic #Anemia ... Diagnosis #Table #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... #Autoimmune #Hemolytic ... #Anemia #Pathophysiology ... #diagnosis #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Hemolysis: • Autoimmune ... Hemolytic Anemias ... (AIHAs) • Alloimmune ... Diagnosis #Algorithm #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... #Autoimmune #Hemolytic ... #Anemia #AIHA # ... Treatment #management #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
• Cold AIHA ... • Alloimmune ... • Drug-induced AIHA ... immune-complex hemolytic anemia ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... (AIHA) "Warm" ( ... idiopathic) - Autoimmune ... (AIHA)"Cold" (usually ... #anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... : Warm AIHA, Cold ... AIHA, Transfusion ... Defects: Sickle cell anemia ... Differential #Diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... cytopenias (ITP, AIHA ... marrow failure with anemia ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Viral infection, autoimmune ... • Symptoms of anemia ... CLL (older) • Autoimmune ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Corticosteroid use • Autoimmune ... Degree of bandemia ... neutrophil #WBC #CBC #hematology ... #pathophysiology
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