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hematology differential hemolytic causes oncology hemolysis algorithm autoimmune leukemia chronic cll extravascular hemeonc intravascular lymphocytic management workup alkaline alp anemias
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... Diagnosis Table ... hemoglobinuria) • Cold Agglutinin ... #Diagnosis #Table ... #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic Anemia ... (AIHA) Pathophysiology ... Autoimmune #Hemolytic #Anemia ... #Pathophysiology ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... • Symptoms of anemia ... anemia • Cold ... disease #hemolytic #anemia ... #hematology #diagnosis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... (AIHAs) • Alloimmune ... #Differential #Diagnosis ... #Algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... - Autoimmune (AIHA ... - Autoimmune (AIHA ... . primary cold agglutin ... #hematology #anemia
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... Symptoms of Hemolytic Anemia ... #Pathophysiology ... #Hemolytic #Anemia ... #hematology #diagnosis
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
), C3d ( - ) WAIHA ... ( +/- ) Cold agglutinin ... Autoimmune #Hemolysis #hematology ... #diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... • Cold AIHA ... immune-complex hemolytic anemia ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... #Aplastic #Anemia ... #diagnosis #oncology ... #hematololgy
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Autoimmune: Warm AIHA ... , Cold AIHA, Transfusion ... Defects: Sickle cell anemia ... #hematology
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