31 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... defects. 1) HELLP ... child * Severe cases ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... defects. 1) HELLP ... child * Severe cases ... Pregnancy #TTPHUS #HELLP ... Obstetrics #OBGyn #Hematology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... and Cholestatic Liver ... #Enzymes #LFTs ... #differential #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Pregnancy - AFLP, HELLP ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... • Vasculitis Coagulation ... Iatrogenic) • Liver ... Diagnosis #Algorithm #Causes ... #Hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... NAFLD, Autoimmune, HELLP ... Differential #Diagnosis #hepatology ... Transaminitis #LFTs
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Preeclampsia, HELLP ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Hepatocellular - Liver ... biliary obstruction, HELLP ... Differential #Diagnosis #Causes ... Acute #algorithm #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Pregnancy - AFLP, HELLP ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Interpretation of LFTs ... • Albumin • Coagulation ... #differential #Hepatology ... transaminitis #LFTs