11 results
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... Function #Tests #LFTs ... #Laboratory #Values ... Interpretation #diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Viral, Ischemia, AIH ... - Viral, AIH ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... Chemistry #Tests #Laboratory ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Drugs • AIH ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Autoimmune: Warm AIHA ... , Cold AIHA, Transfusion ... Defects, Drugs, Liver ... Hypophostphatemia Laboratory ... Differential #Diagnosis #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... If suspected, AIH ... Necrosis) If mild laboratory ... Diagnosis #Management #Hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
) or metabolic liver ... Possible drug-induced liver ... Presence of atypical laboratory ... Hepatitis #Diagnosis #Hepatology ... #AIH
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Alcoholic Hepatitis (AH ... ) or metabolic liver ... Possible drug-induced liver ... Presence of atypical laboratory ... #hepatology #criteria
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... venipuncture sites Laboratory ... DIC • Severe Liver ... treatment #management #hematology
Acute-phase Reactants Synthesized in the Liver 
Positive acute-phase reactants (concentrations increase with acute inflammation)
 - Immune-related
Synthesized in the Liver ... #Synthesized #Liver ... #Synthesis #Hepatology ... #pathophysiology ... #Laboratory