18 results
diagnosis management differential treatment algorithm coagulation hemophagocytic hepatology hlh lymphohistiocytosis nephrology syndrome vasculitis adjusted age alkaline alp ana antibody antinuclear
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... (CVID, WAS), (neurologic ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... diagnosis #algorithm #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
considered in all cases ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... 100 mg/m2) : in case ... emergency, ICU in case ... treatment #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Scl70 (in some cases ... Scl-70 (in some cases ... body-like: - Neurologic ... differential #diagnosis #rheumatology
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