13 results
Pathophysiological mechanisms of diastolic heart failure HFpEF and possible therapeutic interventions.
Hypertension → Overload
Diabetes → Oxidative stress,
Hypertension → Overload ... regulatory reserve → Pulmonary ... #diastolic #heartfailure ... #dchf #hfpef #pathophysiology
Heart Failure with Preserved Ejection Fraction: Management Principles

General Therapeutic Principles:
Reduce the congestive state 
 - Caution
Ejection Fraction: Management ... causing systemic hypertension ... , pulmonary hypertension ... ineffective) #Management ... Diastolic #Treatment #HeartFailure
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
development of HF ... of life; HTN, hypertension ... #CHF #Congestive ... #HeartFailure # ... ACCAHA #Algorithm #Management
Right-Sided Heart Failure - Differential Diagnosis Algorithm
Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
Valves • Pulmonary ... Arterial Hypertension ... • Pulmonary ... Veno-Occlusive Disease #RHF ... #RightSided #HeartFailure
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
Cardiogenic Shock - Management ... hypertension Rx ... 20 mg q6hr) - Hypotension ... #Checklist #CHF ... #Cardiogenic #HeartFailure
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... iron #deficiency #CHF ... #HFrEF #heartfailure ... #diagnosis #management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : Age>60, CKD, CHF ... transfusion • Pathophysiology ... , and CXR with pulmonary ... ) • Fever and hypotension
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Pulmonary Thromboendarterectomy
Chronic Thromboembolic Pulmonary Hypertension
Definition: mean pulmonary-artery pressure > 25mmHg
Hypertension (CTEPH ... Hypertension Definition ... embolism Pathophysiology ... #Hypertension # ... Thromboendarterectomy #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
/Hypertensive emergency ... Etiology: • Pathophysiology ... the brain • CSF ... cell count in the CSF ... Syndrome #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... sepsis), PE, DAH, CHF ... APML #diagnosis #management