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HepatoRenal Syndrome - Pathophysiology

Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ

#HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis
HepatoRenal Syndrome ... amzn.to/34t5DgJ #HRS ... #HepatoRenal #Syndrome ... #Diagnosis #Nephrology ... #AKI
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... (HRS) - Diagnostic ... Criteria HRS-AKI ... Type 2) • HRS-AKD ... #Hepatorenal #Syndrome
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... - Differential Diagnosis ... Hypoperfusion • Hepatorenal ... syndromes • Drugs ... #Acute #KidneyInjury
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... calcineurin inhibitors, hepatorenal ... syndrome) • Vascular ... #KidneyInjury #Differential ... #Diagnosis #nephrology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... you confirmed diagnosis ... CONSIDER INTRINSIC CAUSES ... #Acute #KidneyInjury ... simplified #workup #diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
failure (a.k.a. hepatorenal ... vasculitis - TTP/HUS ... tubular necrosis (causes ... Classification #diagnosis ... #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... - Differential Diagnosis ... Distributive Shock, HRS ... Abdominal Compartment Syndrome ... #nephrology #causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... osmolarity If cause ... pressure • TTP / HUS ... • Cardio-renal syndrome ... #nephrology #causes
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Classification: HRS-AKI ... HRS-Non-AKI (formerly ... #HRS #Hepatorenal ... #Nephrology #Diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Dermatomyositis) AKI ... - Pathophysiology ... output: 200ml/hr ... Management #Summary #causes