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diagnosis management erythematosus joint systemic workup arthritis causes hemolytic signs symptoms algorithm classification dermatology disease msk oncology testing thrombocytopenia vasculitis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
parvovirus B19 infection ... parvovirus B19 infection ... lesions • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Diseases: • Systemic lupus ... deficiency Infections ... #Diagnosis #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... involvement 3% SLE-Related ... Other auto-immune, Infectious ... Lupusreference #SLE ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... lesions Abdominal pain ... ) Blood (75%): Anemia ... symptoms #diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic Anemia ... Autoimmune • ITP • SLE ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... the face (many differential ... Unexplained fever, when infection ... erythematosus #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... Associated - SLE ... #Diagnosis #hematology ... #rheumatology #
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Framework Non-Infectious ... (RA), Systemic lupus ... erythematosus (SLE ... #Diagnosis #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... usually IgG) (e.g. lupus ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... Erythematosus #Diagnosis #Rheumatology
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