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diagnosis rheumatology dermatology erythematosus sle symptoms systemic algorithm causes agglutinin aortitis arteritis autoantibodies classification clinical cold cutaneous dermpath disease gca
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
parvovirus B19 infection ... parvovirus B19 infection ... lesions • Discoid lupus ... #joint #pain #skin ... #rashes #differential
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
insufficiency • Vasculitis ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... Cryoglobulinemia Infectious ... #dermatology #Differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Butterfly rash, Vasculitis ... lesions Abdominal pain ... ) Blood (75%): Anemia ... erythematosus #signs
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
(5%): PAN > GPA ... (3%) • Infections ... #dermpath #dermatology ... #semiology #signs ... pathology #lesions #differential
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Framework Non-Infectious ... Aortitis: • Vasculitides ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... (aPL) 30-45% Differential ... Other auto-immune, Infectious ... autoantibodies #signs ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... such as systemic lupus ... to exclude are infections ... purpura: strong sign ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... - Trauma - Infection ... - Vasculitis ... lesions • Severe pain ... (lupus, RA, Sjogren's
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... • Symptoms of anemia ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... Arthritis: • Joint pain ... lymphopenia, low PLT • Anemia
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