67 results
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... Definition • Pathophysiology ... Expectation • Rx Algorithm ... #Aplastic #Anemia ... #diagnosis #oncology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... , Target Cells ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Differential Diagnosis Algorithm ... History • Bite cells ... Deficiency • Sickle cells ... Differential #Diagnosis #Algorithm ... #causes
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
stored red blood cells ... • chronic anæmia ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Differential #Causes
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... malignancy: • Symptoms ... : B-symptoms, bruising ... hepatomegaly • Labs: anemia ... predominant immature cells
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... • Improve the symptoms ... #oncology #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Differential Diagnosis Algorithm ... Macrocytosis, Target Cells ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Arrhythmias - Differential Diagnosis Algorithm
May present as: palpitations, dizziness, syncope, chest discomfort
Cardiac Causes:
 - Structural
Differential Diagnosis Algorithm ... State: • Anemia ... #Arrhythmias #Cardiology ... Differential #Diagnosis #Algorithm ... #causes
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Reed-Sternberg Cells ... #Causes #Hematology ... #Oncology