48 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... adsorption onto cancer cells ... Syndrome #Diagnosis #Management ... #treatment #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology #treatment ... #decisionaid #cardiology ... #hematology #warfarin
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Syndrome (IBS) - Management ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... Gastroenterology and Hepatology ... gastroenterology #treatment
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... AP, ↑INR, ↑BUN/Cr ... Intrahepatic Cholestasis Management ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... common • Imaging: CXR ... APML #diagnosis #management ... #hematology #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... fluid balance, and CXR ... : No • Treatment ... Transfusion #Reactions #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... Chronic Management ... by a hemophilia treatment ... #treatment #hematology