68 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... • Rheumatic disorders ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... • Metabolic disorders ... Myeloproliferative Disorder ... pancytopenia, blast cells ... #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Myelodysplastic Disorder ... or λ), Smudge Cells ... Amy Chung, MD, MSc ... #hematology #Markers
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Effusions: - Hematologic ... Osteochondroma Hematologic ... #Effusions #causes ... differential #diagnosis #msk
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders ... Myeloproliferative disorders ... adsorption onto cancer cells ... Diagnosis #Management #treatment ... #hematology #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Responsive to Treatment ... growth, response to treatment ... Amy Chung, MD, MSc ... pathophysiology #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
similarly to mast cells ... Myeloproliferative Disorders ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Skull/spine/Pelvis ... • Bone Marrow Disorder ... Fractures #Pathologic #MSK ... #Orthopedics #Causes