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diagnosis rheumatology syndrome treatment dermatology sle summary blood covid19 differential erythematosus hemeonc hemophagocytic hlh leukemia lymphohistiocytosis mds myelodysplastic product reactions
COVID-19: ICU Guidelines for the Non-Intensivist Infection Control Risk Factors for Severe Disease Initial Laboratory Workup COVID-19 Specific Medications Respiratory Cardiac Hematologic Neuro/Sedation #COVID19 #ICU
COVID-19: ICU Guidelines ... Factors for Severe Disease ... Respiratory Cardiac Hematologic ... #criticalcare # ... NonIntensivist #diagnosis #management
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Positive in 60-80% of cases ... Evolution: Chronic disease ... #Summary #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... old, ~10,000 new cases ... #treatment #hematology ... #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Drugs, Unknown cause ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... number of sites of disease ... classification #hematology ... #oncology #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... number of CD34+ cells ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
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