56 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
malignancy: • Symptoms ... : B-symptoms, bruising ... predominant immature cells ... Diagnosis #Algorithm #hematology ... #WBC #Leukemoid
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... Chronic myelogenous leukemia ... pancytopenia, blast cells ... Diagnosis #Algorithm #Causes ... #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lymphoblastic Leukemia ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse
bullous lesions (not shown). These
Leukemic skin Infiltrate ... Acute Myelogenous Leukemia ... cells. ... Images #Clinical #Photo ... #Dermatology #SkinRash
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
of germinative skin ... cells. ... Causes: 1) Exfoliative ... Basophils/Histamine 4) Skin-homing ... #Dermatology #Rash
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... -> AML: Blast crises ... CLL -> Invade Skin ... #Hematology #Oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... Causes: - Idiopathic ... Syndrome #diagnosis #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... : - CLL cells ... workup #oncology #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
similarly to mast cells ... Chronic myeloid leukemia ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils