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diagnosis management dermatology oncology clinical syndrome differential disease symptoms vasculitis workup lupus systemic algorithm arthritis comparison cryoglobulinemia erythematosus hemeonc hemophagocytic
Hypereosinophilia (HE) Summary • Definition • When to Suspect? • A Partial Classification of Hypereosinophilia •
• A Partial Classification ... Presentations • Treatment ... Hypereosinophilia #HE #hematology
Dermatofibroma - Skin-colored to brown papule or nodule - Firm, indurated texture -
Dermatofibroma - Skin-colored ... Male - Dimple sign ... Dermatofibroma #Dermatology ... Benign #Clinical #Photo
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... glucocorticoid treatment ... organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
LcSSc) - distal skin ... thickening Signs ... changes): skin ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bruising • Skin ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(LP) tumour B cells ... Responsive to Treatment ... growth, response to treatment ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
nose chondritis, skin ... vasculitis • Hematologic ... criteria for 1) hematologic ... blood myeloid cells ... Autoinflammatory #Somatic #rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... megaloblastic anemia Treatment ... diagnosis #management #treatment ... #hematology
Symptoms Distinguishing Groups of Cutaneous Drug Reactions IgE-mediated reactions: • Onset minutes to hours into treatment course
to hours into treatment ... Raised off of the skin ... Blistering and/or skin ... Drug #Reactions #dermatology ... clinical #comparison #classification
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
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