28 results
oncology syndrome rheumatology differential chronic hemeonc hemophagocytic hlh lymphohistiocytosis algorithm anemia aplastic causes classification gastroenterology hepatology leukemia lymphocytic mds myelodysplastic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... or basket cells ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis ... workup #oncology #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... (± cirrhosis) w ... months without treatment ... #Hepatology #gastroenterology ... #management #diagnosis
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Irradiation • Cirrhosis ... #Differential #Diagnosis ... #causes #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... lymphocytes, smudge cells ... uw_IMresidency #CLL ... Leukemia #oncology #hematology ... #management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... Consider stem cell ... #management #treatment ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... adsorption onto cancer cells ... #Management #treatment ... #hematology #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Responsive to Treatment ... growth, response to treatment ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... Renal Failure Treatment ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... lymphoma, B-cell ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
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